Among 59 patients with an applicable CAP simultaneous to ST, Spearman’s correlation coefficient was r=0.37, p=0.03.sSupposed FP-LSM patients had also higher rates of SS by CAP(40%vs15%,p=0.04) compared

to non- FP-LSM. Patients with SS as per CAP, had higher median LSM[6.5(4.4-13.6)vs 5.7(3.2-8.7)kPa,p=0.01].The high failure rate (35%) of the M probe that selleck chemicals llc measures concomitantly the CAP, limited the multi-variate analysis for CAP in this population. Conclusion: In type-2 diabetic patients, the presence of severe steatosis presumed by SteatoTest was independently associated to the overestima-tion of liver fibrosis by liver stiffness Ceritinib research buy measurement. Disclosures: Yen Ngo – Employment: BioPredictive Mona Munteanu – Employment: Biopredictive Vlad Ratziu – Advisory Committees or Review Panels: GalMed, Abbott, Genfit, Enterome, Gilead; Consulting: Astellas, Axcan, Pfizer, Sanofi-Synthelabo, Genen-tech, Nycomed Agnes Hartemann-Heurtier – Consulting: Sanofi-Aventis, Pfizer; Grant/Research Support: Lilly Thierry Poynard – Advisory Committees or Review Panels: MSD; Speaking and Teaching: BMS; Stock Shareholder: BioPredictive The following people have nothing to disclose: Hugo Perazzo, Noemi Seurat, Elena Luckina,

Fanny Rutka, Marion Couteau, Sophie Jacqueminet, Denis Mon-neret, Françoise Imbert-Bismut Background/Aims: Diabetes is associated with increased risk of hepatocellular carcinoma (HCC) and disease progression in chronic liver disease but factors associated with diabetes in patients infected with hepatitis B virus (HBV) living in North America (NA) have not been previously studied. Therefore, we set out to determine the rates and factors predictive 上海皓元 of diabetes and impaired fasting

glucose (IFG) in a large multi-ethnic NA cohort of patients infected with HBV. Methods: HBsAg+ adults without liver decompensation, HCC, liver transplant, HIV or current antiviral therapy from 21 US/Canada centers were enrolled. Those with known diabetes or fasting glucose data were included in the analysis. Diabetes was defined by history/medications or fasting glucose >126 mg/dL and IFG as fasting glucose 110-125 mg/dL. Overweight/obese was defined by race-adjusted BMI. Results: 900 patients were included in the analysis: median age 43 years, 51% male, 71% Asian (14% black, 11% white), 81% born outside US/Canada (30% migrated >20 yrs ago). Most whites were born in NA, while 66% of blacks, and 92% of Asians were born in Africa and Asia, respectively. Median BMI (Kg/m2) was 27 in whites, 28 in blacks, 23 in Asians. 27% were HBeAg+, 20% had HBV DNA >10Λ7 IU/mL and 4% had cirrhosis. 70 (8%) patients had IFG and 112 (12%) had diabetes.