The outside micro-locking plate coupled with closed lowering of the treating 5th metatarsal comminuted fracture with severe smooth structure injury has got the features of easy procedure, good security and low infection price Natural biomaterials , that is learn more helpful to the repair of soft issue injury, and the fixation is eliminated early in outpatient center. In conclusion, this surgical treatment works for customers with serious smooth structure injury and comminuted fracture to prevent periosteum stripping. The space occupying is smaller compared to the micro-external fixator, which can be convenient for clients with very early useful exercise. Twenty-four male brand new Zealand rabbits aged six months and weighed (2.0±0.5) kg were randomly divided into empty group, design group and acupotomy group, 8 rabbits in each team. KOA model was founded by modified Videman technique with remaining hind limb extended plaster immobility for 6 days. In acupotomy group, the transfascial points of interest of quadriceps femoris muscle were released by acupotomy beneath the assistance of Jingjin theory for 4 times and once a week, additionally the therapy points include Hedingci, Binwaixia, Binneixia. Blank team and model group had been given ordinarily without input. Seven days after the end associated with intervention, the pennation angle(PA), muscle tissue thickness(MT), cross-sectional area(CSA) and stress ratio(SR) of rectus femoris werinjury in rabbits with KOA, which can be one of many components of acupotomy when you look at the treatment of KOA. Osteosarcoma(OS) and Ewing’s sarcoma (EWS) would be the two most common major cancerous bone tumors in children. The goal of the analysis was to recognize crucial genes in OS and EWS and research their potential pathways. To explore the clinical effectation of the changed Topping-off method in the treatment of multiple lumbar degenerative diseases. From October 2019 to May 2020, 42 clients which underwent customized Topping-off procedure (altered Topping-off team) and 42 customers who underwent multilevel total laminectomy and interbody fusion with screw pole system internal fixation (whole laminectomy group) had been observed and examined. There were 15 men and 27 females into the modified Topping-off group, aged from 28 to 80 yrs old, with on average (59.57±11.85)years old. There have been 14 men and 28 females into the entire laminectomy team, elderly from 45 to 82 yrs old, with an average of (64.26±9.19) yrs old. Aesthetic analogue scale (VAS) and Oswestry Disability Index (ODI) had been evaluated before procedure, a week, 6 weeks and 12 months after operation. The intraoperative loss of blood, incision length, procedure time, postoperative drainage, weight-bearing time, hospitalization time, intervertebral space level, intervertebral age had been considerable variations in VAS scores involving the two groups at 1 week, 6 weeks and 12 days after operation( The applying of customized Topping-off technique into the treatment of multi segmental lumbar degenerative diseases decrease the full total duration of fusion portions, prevent or slow down the degeneration of adjacent portions, and it has an optimistic effect on maintaining the standard movement associated with the multimedia learning back.The applying of altered Topping-off method within the treatment of multi segmental lumbar degenerative diseases decrease the full total amount of fusion segments, prevent or slow down the degeneration of adjacent sections, and it has a positive effect on keeping the standard activity regarding the back. In accordance with 73 clients with center clavicle fracture addressed conservatively, a unique category of center clavicle fracture had been suggested, and the medical aftereffect of synthetic splint in the treatment of center clavicle fracture was seen. Complete 73 clients with center clavicle break treated with plastic splint from September 2018 to August 2020 had been analyzed retrospectively. Most of the customers had been divided in to 4 types in line with the amount of fracture displacement. There were 16 cases of typeⅠ, including 7 guys and 9 females, ranging in age from 18 to 37 yrs old, with a mean of (28.6±7.8) yrs old;12 situations of moderate disease, 3 cases of reasonable infection and 1 case of serious infection. There were 16 situations of type Ⅱ, including 6 men and 10 females, ranging in age from 25 to 49 yrs . old, with a mean of (37.3±9.4) yrs old;5 situations of moderate infection, 8 situations of moderate condition and 3 situations of severe disease. There have been 7 instances of type Ⅲ, including 4 men and 3 females, ranging in age from 33 to 57 yeious displacement and overlapping displacement, therefore the incidence of complications is reasonable. It may be popularized in center.The classification of center clavicle break is much more appropriate into the clinic, which includes a specific clinical guiding value for the variety of treatment options and prognosis of center clavicle fracture. Plastic splint is beneficial when you look at the treatment of center clavicle fracture without apparent displacement and overlapping displacement, therefore the occurrence of problems is low.