A post-illness questionnaire mostly at 2 years later was provided by 28 out of the 42 patients. Results: Post-illness positive score (32.6) was higher than that
of pre-illness (20.5) (P < 0.0001). Post-illness negative score (1.6) was lower than that of pre-illness (12.5) (P < 0.0001). Post-illness PBDS (31.0) was higher than MLN8237 that of pre-illness (7.9) (P < 0.0001). Conclusion: CD dietary education dramatically increased PBDS. PBDS is a useful tool for assessing a dietary intervention of PBD. PBD and PBDS can be modified for a variety of diseases and for national dietary preferences. Key Word(s): 1. Crohn's disease; 2. plant-based diet; 3. vegetarian diet; 4. inflammatory bowel disease Presenting Author: HWANG CHOI Additional Authors: KYU YONG CHOI, BO IN LEE, JEONG SEON JI, KANG MOON LEE, SANG WOO KIM, SOK WON HAN, MYUNG GYU CHOI Corresponding Author: HWANG CHOI Affiliations: OSI-906 order The Catholic University of Korea, The Catholic University of Korea, The Catholic University of Korea, The Catholic University of Korea, The
Catholic University of Korea, The Catholic University of Korea, The Catholic University of Korea Objective: The extent of disease in ulcerative colitis (UC) is important in management and surveillance. Distal UC has been favorable clinical outcome compared with extensive UC. The outcome of ulcerative rectosigmoiditis was not well known. We evaluated the long-term clinical outcome of ulcerative rectosigmoiditis. Methods: The medical records of 238 patients with UC who initially diagnosed and followed more than 1 year DAPT cost at our university hospital from 1991 to 2010 were reviewed retrospectively. The extent of disease divided 4 groups; proctitis (UC-P, n = 114), rectosigmoiditis (UC-RS, n = 45), left-sided (involvement of descending colon, UC-D, n = 35) and extensive UC (UC-E, n = 44). Clinical characteristics, initial severity, and outcome were compared between 4 groups. Results: The age at diagnosis, gender, and follow-up period were not different in 4
groups (mean 41 years of age, 122 male, mean 83 months of follow-up period). The Mayo scores of 4 parameters at initial diagnosis in patients with UC-RS were between those in patients with UC-P and UC-D (p < 0.001). The severity of UC-RS was near to that of UC-D rather than that of UC-P. Although the number and interval of relapse was not different between groups, the number of hospitalization and the rate of colectomy were significantly different between groups (p < 0.001 and p = 0.027, respectively). The usage of drugs was also different between groups (p < 0.001). Conclusion: The long-term clinical outcome in patients with UC-RS was similar as that in patients with UC-D. The Montreal classification for defining the distribution of disease was also reliable in Korea. Key Word(s): 1. Ulcerative colitis; 2.