No significant differences or changes in EBT were found when comparing asthmatics to healthy controls before or after any of the tests. Conclusions: EBT is increased after both EVH and MCT, possibly reflecting a vascular response. This is related

to both the fall in FEV1 and to oral temperature, suggesting an effect on the whole respiratory tract including the oral cavity. No differences in EBT are seen between asthmatics and healthy controls, indicating HDAC inhibitors cancer that the increase in EBT is ;mainly physiological rather than pathophysiological. (C) 2013 S. Karger AG, Basel”
“The output power of InGaN multiple-quantum-well laser diodes (LDs) emitting at 405 nm wavelength is compared for several Al composition in the AlGaN n-cladding layer. The Al composition has been varied from 2% to 6% to study the effect of n-cladding refractive index on threshold current and

slope efficiency of the LDs. As the Al composition in the AlGaN n-cladding PFTα layer increases, both threshold current and slope efficiency decrease. This behavior can be explained by the change in optical field distribution with refractive index of the AlGaN n-cladding layer. It is found that the Al composition of <= 4% would be advantageous for achieving more than 100 mW output power and high level of catastrophic optical damage.”
“Osteogenesis imperfecta is a heterogeneous genetic disorder characterized by bone fragility and deformity, recurrent fractures, blue sclera, short stature, and dentinogenesis imperfecta. Most cases are caused by mutations in COL1A1 and COL1A2 genes. We present a novel splicing mutation in the COL1A1 gene (c. 1875+ 1G>C) in a 16-year-old Brazilian boy diagnosed as a type III osteogenesis imperfecta patient. This splicing mutation and its association with clinical phenotypes will be submitted to the reference database of COL1A1 mutations, which has no other description of this mutation.”
“Our aim was to assess the perceived emotional burden and quality of SBC-115076 life (QOL) in a sample of Greek primary

caregivers of patients with multiple sclerosis (MS).

Twenty-two male and 13 female primary caregivers (mean age 47.3 +/- A 12.4 years), and an equal number of patients with MS, completed the Greek validated version of the hospital anxiety and depression scale (HADS) and the Greek validated version of EuroQOL (EQ-5D). Thirty-five age-, gender-, and education-matched healthy controls were used for comparison.

Caregivers experienced higher degree of anxiety than depression. The mean score of the HADS-A subscale was 9.5 +/- A 4 (range 3-15), and the mean score of the HADS-D subscale was 7.1 +/- A 3.1 (range 2-14). The mean scores of caregivers on both HADS-A and HADS-D were significantly higher than the controls’ (P < 0.0001). Twenty-two caregivers were diagnosed with manifesting anxiety, whereas 12 of them also presented depression. Highly educated caregivers were more prone to manifest increased levels of anxiety and depression.