4% male, 37.6% female) with symptoms of asthma (n=141, 57.1%), allergic rhinitis (n=50, 20.4%), atopic dermatitis (n=29, 11.7%), and urticaria (n=20, 8.1%) were studied. Positive skin prick test to at least one allergen was 58.1%. The most prevalent allergens were tree mix (26%), Alternaria alternata (26%), weed mix (23.6%), Dermatophagoides

farinae (22.9%), Dermatophagoides pteronyssinus (22.9%), milk (21.7%), eggs (20%), and wheat flour (18.3%). Also, common allergens in the patients with different symptoms of allergic selleck AZD9291 disorders were Inhibitors,research,lifescience,medical as follows: asthma (tree mix, weed mix, and Dermatophagoides farinae); allergic rhinitis (Dermatophagoides farinae, tree mix, and Dermatophagoides pteronyssinus); and atopic dermatitis (Alternaria alternata, Dermatophagoides pteronyssinus, and cockroaches). Conclusion: Identifying allergens in each area is necessary and Inhibitors,research,lifescience,medical has an important role in the diagnosis and management of allergic

disorders and possibility of performing immunotherapy. In this study, the most common aeroallergens were tree mix, Alternaria alternata, and weed mix and also the most common food allergens were milk, eggs, and wheat. Considering these Inhibitors,research,lifescience,medical data, appropriate preventive strategies can decrease the cost and morbidity of therapeutic actions. Keywords: Allergens, Children, Skin test Introduction The prevalence of allergic disorders such as atopic dermatitis, allergic respiratory diseases, and food allergy has increased in the last Erlotinib mechanism of action decades and become a major medical concern.1-4 To understand the cause of this trend, researchers have studied such environmental factors as air pollution,2,3,5 decrease in exposure to microbiologic stimuli,6 and changes in dietary habits.7 Inhibitors,research,lifescience,medical Allergy is an overreaction (immune-mediated reaction) to various proteins (allergens),8 first and foremost among which are aeroallergens Inhibitors,research,lifescience,medical (e.g. trees, grasses, weeds, moulds, house dust mites, and animal dander).9 In addition, other factors known to be responsible for the development of atopy

include genetic factors, age of exposure to allergens,9 and number of siblings.10 For the confirmation of the presence of allergy, Carfilzomib the most common diagnostic procedures available are the IgE specific test, food challenge test, and skin prick test (SPT).8,11 The relationship between the results of the SPT and the allergic disease is interpreted by the patient’s clinical history. Allergen selection should be on the basis of the patient’s symptoms, environmental exposures, occupational situation, age, and hobbies and the clinical history of the patient must be considered in the interpretation of the allergy test.12 In fact, the SPT is utilized to verify or leave out sensitization to allergens.13 The aim of this study was to determine the common allergens in children by means of the SPT results.