57 Studies from East London reported a low incidence of IBD in Bangladeshi migrants in the 1980s.37,38 A more recent study has shown an increase in CD incidence in Bangladeshi migrants from 2.3 (1981–1989) to 7.3 (1997–2001), and an increase in UC incidence from 2.4 (1981–1989) to 8.2 (1997–2001).39 In this study, most UC patients (13 of 16) were born in Bangladesh as compared to 8/19 CD cases.

These increases in IBD coincided with a decrease in the incidence of abdominal tuberculosis.39 In the Northwest of England a recent report described a higher prevalence and lower mean age at diagnosis of UC in the adult South Asian population than the Caucasian population.58 In Canada, there have been a number of recent studies from British Columbia.42,59,60 A pediatric study from Vancouver showed a higher prevalence of both UC and CD in the pediatric South Asian (Indian) population compared with other ethnic groups, including buy Selumetinib Caucasian children. The majority (84%) of the South Asian patients were the children of immigrants.42

These South Asian patients had a male predominance and more extensive colonic disease than the non-South Asian patient population.42 A single center study from KU-57788 purchase Vancouver reported rates of hospitalization in CD patients of Caucasian, South Asian (East India, Pakistan, Sri Lanka) and Pacific Asian (Chinese, Japanese, Korean) ethnicity at 7.8, 7.7 and 2.1 per hundred thousand pro rata for each ethnicity of the total Vancouver population, respectively. Rates of hospitalization in UC patients were higher in

South Asians (6.8) than Caucasians (5.1) and Pacific Asians (0.8).59 An earlier study from Vancouver reported the mean duration of residence in Canada for South Asian (mostly Indian) migrants before developing IBD was 8.9 years for CD and 13.5 years for UC.60 There was also an older mean age of patients born overseas (mostly India) than those born in Canada.60 In a study from Quebec, a lower proportion of people reporting to be immigrants was an independent predictor of lower CD incidence rates.61 In the United States, studies on different ethnicities in IBD have mainly reported on the African American Dapagliflozin and Hispanic populations;62–65 however, some studies have included Asian data.66 In southern California, prevalence rates for Asians (5.6) and Hispanics (4.1) were much lower than those for Caucasians (43.6) and Afro-Caribbeans (29.8).41 A recent study from Sweden found a decreased incidence of IBD in immigrants (including Asia) compared to native-born Swedes. This decreased incidence did not persist for the local-born children of Asian immigrants.43 A recent study of national hospital discharge data from 500 hospitals in North America calculated separately for different race groups the change in the proportion of hospitalizations for IBD between 1994 and 2006.