al state. However, two of the six patients who had metastases in our study best CONFIRMS had dumplings GW 791343 P2X receptor antagonists and agonists tchen cut smaller than 5.7 mm value, and one patient had no lymph node involvement. Thus, the M Possibility of metastasis can not be ignored, even in the case of small pulmonary nodules, or in patients with negative lymph node status. The question of how often or how long thoracic CT scan should be performed remnants. With regard to the optimal timing of follow-up chest CT indefinite dumplings tchen, 3 to 6 months apart proved to be reasonable in the kinetics of tumor growth of adenocarcinoma. Another issue is the administration of adjuvant chemotherapy. In our study, patients in the metastatic group again U l FOLFOX4 adjuvant chemotherapy Ngeren intervals of metastases compared to those who did not get to develop it, although the difference was not statistically significant.
This seems to be the suppression and concealment of FOLFOX4 chemotherapy for lung metastases. Patients, the FOLFOX4 chemotherapy for a chest CT should l Longer period be pursued. The number of patients ultimately best CONFIRMS metastases was too small to establish a monitoring of the guidelines, but we recommend the following based on JTP-74057 871700-17-3 our findings. In patients who have again U 5-FU adjuvant chemotherapy or no adjuvant chemotherapy, the median time to development of distant metastases 4.55 months and the interval is not l Longer than 6 months. Therefore, if any Change in the interval L for recession Indefinite surveillance chest CT is feasible at 3, 6 and 12 months after initial CT in high-risk group who did not have back u FOLFOX4 chemotherapy.
On the other hand, for patients who again U FOLFOX4 adjuvant chemotherapy, the median time until the development of distant metastases 15.4 months and the minimum was 6 months at least. Thus, the surveillance chest CT is not n TIG, be taken within 6 months after chemotherapy. The monitoring can be started six months after the first CT, then 3, 6, 12 and 18 months after the second CT, if it does not Change in the interval group with a high risk that again u FOLFOX4 chemotherapy. In the group with low risk, the monitoring of chest CT scans 6 and 12 months after the first CT scan will be taken, and if it is not significant Change, monitoring k Can be discontinued. Our study has some RESTRICTIONS Website will. First, the heterogeneous patient population.
Certainly nnte k The incidence of lung metastases slightly h Ago in patients U thoracic CT again have w During the follow-up period than patients who again U chest CT on the one hand, because it seems that the chest CT was performed for some unusualreasons, as an increase in CEA and dilute Chtige findings on positron emission tomography-computed tomography. The main objective of this study was, however, the H Frequency and characteristics of lung metastases between the real indeterminate lung nodules in patients with rectal cancer, which is why we only included patients is analyzed with dumplings tchen found studying indeterminate lung, independent Ngig whether initially she underwent Highest chest CT or sp ter. Thus, the heterogeneity t of Bev Lkerung important in our study did not affect the validity of logical analysis. Second, too many patients were excluded because of the absence