ConclusionSmoking cessation does not appear to be associated
with a substantial short-term increase or decrease in health-care use after adjusting for pre-cessation Selumetinib datasheet morbidities.”
“Objective: Analyses comparing randomized to nonrandomized clinical trials suffer from the fact that the study populations are usually different. We aimed for a comparison of randomized clinical trials (RCTs) and propensity score (PS) analyses in similar populations.
Study Design and Setting: In a systematic review, we “”meta-matched”" RCTs and PS analyses that compared the off- and the on-pump technique in coronary artery bypass grafting. “”Meta-confounders”" were summarized in a “”meta-propensity score”" and were used for “”meta-matching.”" We compared treatment effects between SYN-117 in vivo RCTs and PS analyses for 10 previously defined binary clinical outcomes in this “”meta-matched”" population as differences in “”meta-odds ratios.”"
Results: For all clinical outcomes, the estimated differences in “”meta-odds ratios”" were below an absolute value of 0.15, all confidence intervals included the null.
Conclusions: In our example, treatment effects of off-pump versus on-pump surgery from RCTs and PS analyses were very similar in a “”meta-matched”" population of studies, indicating
that only a small remaining bias is present in PS analyses. (C) 2011 Elsevier Inc. All rights reserved.”
“Pseudo-aneurysms involving the coeliac artery caused by tuberculosis infection are extremely rare and are highly susceptible to rupture.(1) It’s difficult to make the correctly diagnosis preoperative and select reconstructive procedures. We report a case of tuberculous pseudo-aneurysm in the abdominal aorta involving the coeliac artery. The active phase of the tuberculous makes it impossible to perform open surgery, so endovascular percutaneous treatment was performed, inflow to the pseudo-aneurysm was excluded by Selleck AICAR placing a custom-made stent graft at the coeliac artery orifice. The patient recovered very well and was prescribed anti-tuberculosis treatment for up to 6 months.
Endovascular repair for tuberculous pseudo-aneurysm may be a life-saving option, covering the coeliac artery with stent graft is considered safe and suitable. (C) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.”
“Objectives: Ischemic postconditioning (PC) with “”stuttering”" reintroduction of blood flow after prolonged ischemia has been shown to offer protection from ischemia reperfusion injury to the myocardium and brain. We hypothesized that four 20-s pauses during the first 3 min of standard CPR would improve post resuscitation cardiac and neurological function, in a porcine model of prolonged untreated cardiac arrest.
Methods: 18 female farm pigs, intubated and isoflurane anesthetized had 15 min of untreated ventricular fibrillation followed by standard CPR (SCPR).