Nature 1998, 396: 580–584.PubMedCrossRef 20. Ning S, Fuessel S, Kotzsch M, Kraemer K, Kappler M, Schmidt U, Taubert H, Wirth MP, Meye A: siRNA-mediated

down-regulation of survivin SHP099 purchase inhibits bladder cancer cell growth. Int J Oncol 2004, 25: 1065–1071.PubMed 21. Zenke K, Kim KH: Novel fugu U6 promoter driven shRNA expression vector for efficient vector based RNAi in fish cell lines. Biochem Biophys Res Commun 2008, 371: 480–483.PubMedCrossRef 22. Nagao A, Zhao X, Takegami T, Nakagawa H, Matsui S, Matsunaga T, Ishigaki Y: Multiple shRNA expressions in a single plasmid vector improve RNAi against APO866 price the XPA gene. Biochem Biophys Res Commun 2008, 370: 301–305.PubMedCrossRef 23. Song H, Xin XY, Xiao F, Wang DT, Yue QH, Han X: Survivin gene RNA interference inhibits proliferation, induces apoptosis,

and enhances radiosensitivity in HeLa cells. Eur J Obstet Gynecol Reprod Biol 2008, 136: 83–89.PubMedCrossRef 24. Rödel F, Hoffmann J, Distel L, Herrmann M, Noisternig T, Papadopoulos T, Sauer R, Rödel C: Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer. Cancer Res 2005, 65: 4881–4887.PubMedCrossRef 25. Zhen HN, Li LW, Zhang W, Fei Z, Shi CH, Yang TT, Bai WT, Zhang X: Short hairpin RNA targeting survivin inhibits growth and angiogenesis of glioma U251 cells. Int J Oncol 2007, 31: 1111–1117.PubMed 26. Congmin G, Mu Z, Yihui M, Hanliang L: Survivin–an attractive target for RNAi in non-Hodgkin’s lymphoma, Daudi cell line as a model. Leuk Lymphoma 2006, 47: 1941–1948.PubMedCrossRef 27. Jiang G, Li J, Zeng Z, Xian L: Lentivirus-mediated gene therapy by suppressing survivin in BALB/c nude mice bearing oral selleck products squamous cell carcinoma. Cancer Biol Ther 2006, 5: 435–440.PubMedCrossRef 28. Chen Z, Liang K, Xie M, Wang X, Lü Q, Zhang J: Novel ultrasound-targeted microbubble destruction mediated short hairpin RNA plasmid transfection targeting survivin inhibits gene expression and induces apoptosis of HeLa cells. Mol Biol Rep 2009, 36: 2059–2067.PubMedCrossRef 29. Shimamura M, Sato

N, Taniyama Y, Yamamoto S, Endoh M, Kurinami H, Aoki M, Ogihara T, Kaneda Y, Morishita R: Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound. Gene Ther 2004, 11: 1532–1539.PubMedCrossRef 30. Boussif O, Lezoualc’h F, Zanta MA, Mergny BCKDHA MD, Scherman D, Demeneix B, Behr JP: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo : polyethylenimine. Proc Natl Acad Sci USA 1995, 92: 7297–7301.PubMedCrossRef 31. Kircheis R, Wightman L, Schreiber A, Robitza B, Rössler V, Kursa M, Wagner E: Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 2001, 8: 28–40.PubMedCrossRef 32. Das A, Tan WL, Smith DR: Expression of the inhibitor of apoptosis protein survivin in benign meningiomas. Cancer Lett 2003, 193: 217–223.