Before 8, 32, 8 and 16 g / ml, suggesting Rivaroxaban Xarelto the diversity ECV when the molecular species considered. The results were similar for voriconazole: LCA Individual VGI, and VGII VGIV isolates was 0.12, 0.5, 0.12 and 0.25 g / ml for itraconazole, had only the VGI isolates a lower total cost than that kobilanz. For posaconazole, VGI isolates again had a low ECV isolated to 0.5 g / ml and the lowest ECV VGIII to 0.12 g / ml Interestingly, the isolates VGIIc not solely responsible for the movement of the LCA upward, like a big e VGIV number of isolates had high MIC values for posaconazole. 4th Discussion In this paper we have confinement azole MIC values for the gr-Run collection of C. gattii molecular type founded VGIV isolated to date, and the gr-Run collection of isolates from the advent PNW Minus any available isolates VGIIc . We established the first vorl Ufigen LCA azoles for C. gattii isolates in general and for specific molecular types and subtypes. We have best Firmed that GM had MIC values between the different subtypes and consequently, so were the VCE, although the current database is small, so the clinical significance of the values may not correlate with statistical significance. Taken together, these results justify the need for a big s global database of C. gattii MIC values for further validation of these variables. The big E at the molecular genetic diversity of C. gattii types suggests that different molecular species, at least the varieties usually represent cryptic species. If true, the creation of a single breakpoint specific antifungal for all isolates of C. independent Ngig gattii molecular type k Nnte to a breakpoint result is correct, it is known that there will be significant differences in the reqs Susceptibility of antifungal fungal species. Our results show there also the distribution of molecular weight grades may be insufficient in isolates to represent the differences in sensitivity. Studies or geographical subpopulations as genetic isolates and VGIIb VGIIc can not lead repr Sentative GM MIC values for their molecular type parent. Because isolates and VGIIb VGIIc are clonal, then put It with a PH H phenotype of tolerance Ago as azoles has in Bev Become lkerung be distributed fixed. There is evidence that people in the American Northwest VGII not the only clone of C. gattii populations expand, there is m Possible that h Here MIC values were GM or be mounted in other populations, particularly if the genes genetically genes associated benefits for special niche in the clonal expansion. We have shown that voriconazole is good in vitro activity of t against C. gattii has Similar to the activity T shown by others. However, the overall survival GM MIC value for posaconazole was significantly h Ago than for posaconazole in another global study to be seen. This can be by the prevalence of isolates and VGIIc VGIV in our collection, which were a small minority in the other study, which tend to be explained to the h Chsten MIC values of posaconazole Be rt. Because data is lacking on the clinical results after treatment of fungal infections and pharmacokinetic / pharmacodynamic data for many antifungals, LCA is set to replace the values of breakpoint introduced.