The effective investments on Doxil and Abraxane,

as well as on the other mentioned successful products, are prime examples of this practice. 7. Conclusions and Future Promises Despite the issues nanomedicine still has to face, investments in this market are predicted to increase. New applications of nanomedicine have been demonstrated, and the resulting expansion of the Inhibitors,research,lifescience,medical potential market makes the risk more appealing. Ferocious financial collapse elevated sunk costs of the essential R&D process, tricky access to funds, uncertainty of expected returns, and the extremely meticulous, and lengthy FDA regulatory process has not deterred the investors’ community. On the other hand, the promises of great future potential developments

in the different market segments and high returns connected Inhibitors,research,lifescience,medical to the high risk of the innovation investments make this market still considerably attractive. Compared to the 2007 benchmark, Inhibitors,research,lifescience,medical VCs in 2009 decided to double their investments in this sector, at the expenses of the information technology market. The fact that nanomedicine dominates the VC funding in the healthcare market is surely a good predictor of the bright future landscape of expansion of this promising area of research. Moreover, good returns Inhibitors,research,lifescience,medical could even be the result of more accurate assessments of the investments’ risks. A pharmacoeconomic analysis would allow the efficient allocation of the monetary resources and the maximization of the highest health return at the lowest costs. A cost-effectiveness analysis (CEA)

is structured with a comparison of the costs and effects of two or more treatments, which are under examination. Whereas in the very early stage of the drug development cycle the high learn more failure rate for novel drug molecules is largely due to a not adequate therapeutic index, in the clinical development Inhibitors,research,lifescience,medical phase, this rate originates from economic reasons. Therefore, the development of unsuccessful drugs has to be abandoned very fast, in order to Urease save resources for more promising compounds. This saving is obtained through an accurate economic evaluation performed in the early stages of the development process. The benchmark is represented by life-years saved by the investigated nanotherapeutic; if a nano-enabled therapy does not save sufficient life-years to break-even, it should not be developed further [35]. The major limit to the success of this kind of analysis is given by the scarcity of clinical data concerning nanomedicine. The best solution to this issue is collaboration.