Two previously not recognized cases with Anderson-Fabry disease were identified.
Our study is the first showing that a diagnosis of Anderson-Fabry disease can be missed even in patients who undergo kidney transplantation. Case-finding strategies may be considered a useful tool for diagnosis of this rare disease that may be somewhat more prevalent among kidney transplant recipients compared with dialysis populations.”
“Objectives: To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and selleck chemicals to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).
Methods and results: 589 patients (419 Caucasian,
120 South Asian, 50 other) from the PREDICT Study were investigated. All patients were asymptomatic for GSK2118436 mouse coronary disease and had established T2DM. CACS, lipids, lipoproteins, inflammatory markers, insulin resistance and PON1 activity, concentration and Q192R and L55M genotypes were measured. Independent associations were: 1) PON1 activity negatively with insulin resistance, triglycerides and PON1-55 genotype and positively with PON1-192 genotype; 2) PON1 concentration negatively with Caucasian ethnicity, duration of diabetes and statin use and positively with plasma creatinine and PON1-192 genotype. There was no association between CACS see more and any of the PON1 activity, concentration or genotype and this finding was not different in the various ethnic groups within the PREDICT study.
Conclusion: PON1 is modulated by a number of factors, some of which are reported here for the first time, including ethnicity and insulin resistance in subjects with T2DM. No association
between CACS and PON1 was found.”
“The oscillation of a weld pool surface makes the fluid flow motion quite complex. Two-dimensional results cannot reflect enough information to quantitatively describe the fluid flow in the weld pool; however, there are few direct three-dimensional results available. In this paper, we describe a three-dimensional reconstruction method to measure weld pool surface features based on a single high-speed camera. A stereo adapter was added in front of the high-speed camera lens to obtain two images in the same frame from different view points at the same time. According to machine vision theory, three-dimensional parameters can be reconstructed based on two such images. In this work, three-dimensional velocity fields have been obtained using this method. Based on the calibration technique employed, the associated error is estimated to be less than 11.4%. Quantitative experimental results are useful for understanding the flow pattern, and possibly for controlling the flow of liquid in the weld pool. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.