What he came up with selleck chem Ponatinib was the LGCP which he initially named Total Vertical Gastric Plication, initially tested in animal models (especially sheep) and subsequently applying it to his volunteer patients. First results were published in 2006, and in 2007 a series of 100 consecutive patients were published, successfully placing LGCP on the map and adding it to the armament for the treatment of Morbid Obesity. There is currently ongoing debate on the application of LGCP. The operation itself carries many potential advantages when compared to LSG, mainly due to the fact that there are no anastomotic lines and the risk of leak from a staple line is inherently inexistent.

However, there are currently relatively few publications from authors performing the LGCP, resulting on very few data concerning the results as well as the complication rate of the LGCP, especially when compared to the LSG which has been extensively researched. This fact leads to distrust from the part of the international surgical community, and also led the American Society for Metabolic and Bariatric Surgery to issue a statement in March 2011, containing the following recommendations [7]. Gastric plication procedures should be considered investigational at present. This procedure should be performed under a study protocol with third-party oversight (local or regional ethics committee, institutional review board, data monitoring and safety board, or equivalent authority) to ensure continuous evaluation of patient safety and to review adverse events and outcomes.

Reporting of short- and long-term safety and efficacy outcomes in the medical literature is strongly encouraged. Drug_discovery Data for these procedures should also be reported to a program’s center of excellence database. Any marketing or advertisement for this procedure should include a statement to the effect that this is an investigational procedure. The aim of this study is to review current publications on LGCP especially reported complications and results on excess weight loss (EWL). No other published reviews on Gastric Plication or Laparoscopic Greater Curvature Plication were found during research of the literature, which makes this an original study. 3. Method Online literature research and current library-based peer-reviewed journals review. Online search engines employed are as follows: Medline/PubMed, Google Scholar, and SciVerse. Key words are as follows: Gastric Plication, Laparoscopic Gastric Plication, Laparoscopic Greater Curvature Plication, (LGCP), and Total Vertical Gastric Plication, (TVGP).