Figure ​Figure44 shows the mean data in the STAI-G-State questionnaire in the in the experimental group and the control group divided into the two times of measurement. Figure 4 Mean and standard errors in the STAI-G-State questionnaire

for the experimental group (EG) and the control group (CG) for time of measurement 1 (T1) and time of measurement 2 (T2). STAI-G-Trait The ANOVA revealed no significant main effect for group (F(1, 48) = 1.72) or for time of measurement (F(1, 48) = 2.85). The interaction between group and time of measurement (F(1, 48) = 4.76, P < 0.035) was significant. The mean data in the experimental group decreased from Inhibitors,research,lifescience,medical the T1 to T2, while the data in the control group increased from T1 to T2. Figure ​Figure55 shows the Inhibitors,research,lifescience,medical mean data in the STAI-G-Trait questionnaire in the experimental group and the control group divided into the two times of measurement. Figure 5 Mean and standard errors in the STAI-G-Trait questionnaire for the experimental group (EG) and the control group (CG)

for Inhibitors,research,lifescience,medical time of measurement 1 (T1) and time of measurement 2 (T2). Discussion The main aim of this pilot study was to investigate for the first time the efficacy of an advanced version of EMDR according an intervention of anxiety. Between two times of measurement, the experimental group received an intervention of 1–2 h with respect to their anxiety with the wingwave method, whereas no intervention was employed to the control group. All participants Inhibitors,research,lifescience,medical were asked at both times of measurement to self-generate the emotion of anxiety via the recall of an autobiographical selleck memory. Previous studies have

already demonstrated that the self-generation of an emotion is an appropriate way to induce an emotion like anxiety (e.g., Damasio et al. 2000; Rathschlag and Memmert 2013). We investigated the intensity Inhibitors,research,lifescience,medical of anxiety, the physical performance under the emotion of anxiety and the state and trait anxiety with the STAI (Laux et al. Nature Reviews Clinical Oncology 1981) for both groups and for both times of measurement. First of all, the results demonstrated that the intensity of anxiety did not differ at T1 between both groups and decreased from T1 to T2 in the experimental group but not in the control group. In this respect, we provided evidence for our hypothesis that the wingwave method can help to decrease the intensity of anxiety concerning to the respective anxious memories and their recall, and to make the recall more difficult. This result is in line with several studies that have found that making eye movements (EMDR) while retrieving visual images of negative autobiographical memories reduces their vividness and emotional intensity (e.g., Smeets et al. 2012). In addition, Engelhard et al.