analysis R: A language and environment for statistical computing (R Development Core Team (2008); R Foundation for Statistical Computing, Vienna, Austria) was used for statistical analysis. Results were analyzed by one-way ANOVA and considered significant at p < 0.05. ALK inhibitor Sequence analysis and accession number The 16S ribosomal gene sequence was analyzed using the Blast server for identification of Procaryotes ( http://bioinfo.unice.fr/blast/). Sequence similarity searches were carried out using Basic Local Aligment Search Tool (BLAST) on the JGI website ( http://www.jgi.doe.gov/). Multiple alignments were obtained using the CLUSTALW2 program on the EMBL-EBI web site ( http://www.ebi.ac.uk/). The tool TreeTop of GeneBee Molecular Biology Server was used for phylogenetic tree construction ( http://www.genebee.msu.su/genebee.html). The partial nucleotide sequence of the tdc locus and the 16S ribosomal DNA sequence of L. plantarum IR BL0076 are available in the GenBank database under the accession
number [GenBank : JQ040309] and [GenBank : JX025073] respectively. Acknowledgements We are grateful to Benoît Bach from Inter-Rhône for providing the Lactobacillus plantarum strain IR BL0076. Mass spectrometry analyses were performed by the Lipides-Arômes platform, UMR FLAVIC, INRA Dijon. Electronic supplementary material Additional file 1: Sequence FK228 solubility dmso alignment of TyrDC from L. brevis and L. plantarum . (DOC 31 KB) References 1. Silla Santos MH: Biogenic amines: their importance in foods. Int J Food Microbiol 1996, 29:213–231.PubMedCrossRef 2. Bauza T, Blaise A, Teissedre PL, Cabanis JC, Anacetrapib Kanny G, Moneret-Vautrin DA, Daumas F: Les amines biogènes du vin: metabolisme et toxicité. Bulletin de l’OIV 1995, 68:42–67. 3. Hannington E: Preliminary report on tyramine headache. Br Med J 1967, 2:550–551.PubMedCrossRef 4. Marques AP, Leitao MC, San Romao MV: Biogenic amines in wines: influence of oenological factors. Food Chem 2008, 107:853–860.CrossRef 5. Konings WN, Lolkema JS, Bolhuis H, Van Veen HW, Poolman B, Driessen AJM: The role of transport processes
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