The initial regenerated PFTα film consisted of alpha-helix and random coil components. The aqueous ethanol treatment of the film resulted in significant increase in
beta-sheet component and improvement of water resistance of the film. This effect was strongly dependent on ethanol concentration, and 60-80%, (w/w) ethanol was most effective. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 116:461-467,2010″
“Study Design. Case report.
Objective. We report a rare case of postradiation sarcoma of the cervical spine 30 years after treatment for thyroid cancer.
Summary of Background Data. The reported case is a 66-year-old man with a history of thyroid cancer treated with surgery and radiotherapy at the age of 36 years. He was disease-free for 30 years, but then developed left upper limb weakness and numbness. Magnetic resonance imaging showed a homogeneously enhanced mass lesion with cystic parts involving the C4 vertebral body and occupying the left side of the spinal canal with extension to the paraspinal space through
the neural foramen.
Methods. Using staged posterior and anterior approaches, gross total tumor excision, C4 corpectomy, and spinal fusion were achieved.
Results. The histologic diagnosis revealed sarcoma that was immunoreactive to vimentin and focally to S100 and O13 antibodies. Radiation-induced sarcoma should be suspected in patients who have received radiation Napabucasin treatment previously and present with new neurologic symptoms and signs in the irradiated area. The patient’s muscle power returned to 5/5, except for the left upper extremity, which
reached 2/5; he was free from recurring symptoms during the follow-up period.
Conclusion. Because of advancements in diagnostic techniques and therapeutic methods, more patients survive primary cancer, and therefore an increase in the number of cases of postradiation sarcoma is expected. Postradiation A-1210477 molecular weight sarcomas have extremely long latent periods, and one should therefore always keep in mind such a complication of previous radiation treatment.”
“Objective-To compare 1-year outcomes after lateral fabellar suture stabilization (LFS) and tibial plateau leveling osteotomy (TPLO) for the treatment of dogs with cranial cruciate ligament disease.
Design-Randomized blinded controlled clinical trial.
Animals-80 dogs with naturally occurring unilateral cranial cruciate ligament disease.
Procedures-All dogs were randomly assigned to undergo LFS (n = 40) or TPLO (40). Clinical data collected included age, weight, body condition score, history information, stifle joint instability, radiographic findings, surgical findings, and complications.